Spatial memory deficits in a virtual reality eight-arm radial maze in schizophrenia
نویسندگان
چکیده
منابع مشابه
Spatial memory deficits in a virtual reality eight-arm radial maze in schizophrenia.
Learning and memory impairments are present in schizophrenia (SZ) throughout the illness course and predict psychosocial function. Abnormalities in prefrontal and hippocampal function are thought to contribute to SZ deficits. The radial arm maze (RAM) is a test of spatial learning and memory in rodents that relies on intact prefrontal and hippocampal function. The goal of the present study was ...
متن کاملSpatial memory impairments in amnestic mild cognitive impairment in a virtual radial arm maze
OBJECTIVE This study aims to apply the virtual radial arm maze (VRAM) task to find spatial working memory and reference memory impairments in patients of amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD). Spatial memory functions between aMCI converters and nonconverters are also compared using VRAM results. METHODS We assessed the spatial memory in 20 normal controls, 20...
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ژورنال
عنوان ژورنال: Schizophrenia Research
سال: 2012
ISSN: 0920-9964
DOI: 10.1016/j.schres.2011.11.014